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Selenium levels in the body depend on the characteristics of the population and its diet, geographic area, and soil composition

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Therefore, GSH degradation (but not GSH per se) contributes to cysteine pool which regulates mTORC1 pathway and the ISR in HepG2 cells

Ferroptosis could be a new strategy for CRPC combination therapy Multiple forms of DNA damage, including base damage, single-strand breaks, and double-strand breaks, can be directly caused by ionizing radiation [51], Additionally, it can radioactively break down water molecules within cells and trigger oxidative enzymes to release highly reactive oxygen and hydrogen peroxide radicals, among other ROS, which can impact proteins, lipids, and nucleic acids in a dose-dependent manner [52]