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Targeting XIAP and ARC (apoptosis repressor with caspase recruitment domain) Overcomes Imatinib Resitance In Blast Crisis CML Cells

Furthermore, Ras-selective lethal 3 (RSL3) and the 5,6-dihydro-2H-pyrano[3,2-g]indolizine (DPI) class of luminogen (DPI, also known as ML162) are known as class 2 ferroptosis inducers that directly inhibit GPX4 enzymatic activity [91,93]