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To determine whether targeting riboflavin processing has in vivo antileukemic efficacy, we took advantage of a previous in vivo CRISPR screening platform established in our laboratory, which employed a 200 gene library enriched for AML dependencies, and which included sgRNAs targeting RFK 24

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Melinda Wharton, a senior official at the National Center for Immunization and Respiratory Diseases, a division of the Centers for Disease Control and Prevention