mutations of glutathione s-transferase

mutations of glutathione s-transferase π: a potential role in antitumor therapy | DDDT RCSB PDB - 22GS: HUMAN

Name: mutations of glutathione s-transferase π: a potential role in antitumor therapy | DDDT RCSB PDB - 22GS: HUMAN
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RCSB PDB 22GS: HUMAN GLUTATHIONE S TRANSFERASE P1 1 Y49F MUTANT Frontiers Case report: A Chinese patient with glutathione synthetase deficiency and a novel glutathione synthase mutation Frontiers Glutathione S Transferases: Role in Combating Abiotic Stresses Including Arsenic Detoxification in Plants The role of glutathione S transferase in anti cancer drug resistance Oncogene

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Sechi G, Deledda MG, Bua G, Satta WM, Deiana GA, Pes GM, Rosati G

mutations of glutathione s-transferase : a potential role in antitumor therapy | DDDT RCSB PDB - 22GS: HUMAN

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202,203 Essentially, the imported disulphide-containing proteins undergo cathepsin-catalysed degradation in the lysosome, leading to the formation of cystine, which is then effluxed by the cystinosin transporter into the cytosol, where it is reduced to cysteine in a process that requires NADPH, leading to the formation of oxidised glutathione