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Cartilage: Has no direct blood supply Relies on diffusion for nutrient delivery Contains relatively few cells (chondrocytes) Has low regenerative capacity Chondrocytes are responsible for: Producing collagen (primarily type II) Producing proteoglycans such as aggrecan Maintaining extracellular matrix structure When chondrocytes become dysfunctional due to inflammation, mechanical stress, or aging, cartilage degradation accelerates

The agency noted that the firm had ceased drug production and distribution and initiated a voluntary recall on July 30, 2025, for products with potential microbial contamination

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