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Adverse Reactions/Side Effects The following clinically significant adverse reactions are described elsewhere in the labeling: Spinal or epidural hematomas [see Warnings and Precautions (5.1)] Hemorrhage [see Warnings and Precautions (5.2)] Renal impairment and bleeding risk [see Warnings and Precautions (5.3)] Body weight less than 50 kg and bleeding risk [see Warnings and Precautions (5.4)] Thrombocytopenia [see Warnings and Precautions (5.5)] 6.1 Clinical Trials Experience Because clinical trials are conducted under widely varying conditions, adverse reaction rates observed in the clinical trials of a drug cannot be directly compared to rates in the clinical trials of another drug and may not reflect the rates observed in practice

If accuracy at low doses concerns you, reconstituting with 2mL gives you more readable volumes at the cost of requiring split draws at 8mg and above

Every time you puncture the vial's rubber stopper with a syringe, you create a potential entry point for airborne bacteria

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