glutathione peroxidase 1 brain GPX1 and Its Dichotomous Roles in Cancer Glutathione peroxidase 4: a new

& Combating COVID-19 and Building immune resilience: a potential role for magnesium nutrition

Annu Rev Pharmacol Toxicol 44:32547, PMID: 14744249 Holmgren A, Lu J (2010) Thioredoxin and thioredoxin reductase: current research with special reference to human disease

Neurons of the CNS are very active in oxidative metabolism, as they are constantly exposed to lowtomoderate levels of ROS, and these species are removed by antioxidants (melatonin, vitamin D, vitamin E, glutathione) and antioxidant enzymes (superoxide dismutase, catalase, glutathione peroxidase, etc.)

Another advantage is that the present invention enables administration of a larger quantity of either GSH of methylcobalamin in a single dose than other forms of non-parenteral administration as well as enabling incremental adjustment of doses for children and adults