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Primary efficacy and safety of mirikizumab in moderate to severe Crohns disease: results of the treat-through VIVID 1 study [abstract OP05]

Baillie and Kassahun (1994) state that it seems likely that many xenobiotics with carbamate, formamide, urea, or sulfonylurea functionalities will undergo metabolic transformation to reactive isocyanates and that reversible conjugation to the latter short-lived, potentially toxic intermediates with GSH may play an important role in mediating the disposition and adverse effects of the parent compounds in vivo. 10.17.5.2

In both patients with AF and in angiotensin II-induced AF mouse models, increased infiltration of immune cells such as neutrophils, macrophages, and monocytes in the atrial tissue can be detected (148150)