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doi: 10.1177/1073858407308518 158 BannaiS

A review of the frequency and impact of periodontal disease in dogs

Clinical evidence pertaining to migraines, oxidative stress, and neurogenic inflammation, along with experimental evidence of topiramates antioxidative and anti-inflammatory effects, provide strong hypothetical support for the idea that topiramate may treat migraines by blocking oxidative stress and neurogenic inflammation pathways