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Control cells exhibited a robust SAC, with a median mitotic arrest time of approximately 715 min, whereas BubR1-depleted cells completely lost checkpoint function, exiting mitosis within 20 min (Fig

Lipid peroxidation produces huge amounts of free radicals

The melanoma-associated cancer-testis (CT) antigen (MAGE) is reactivated due to DNA hypomethylation in melanoma and colorectal cancer, which promotes the development of melanoma and colorectal cancer (Kim et al., 2006)