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They bind to specific receptors on cells and trigger cascades that affect hormones, growth, inflammation, metabolism, or nerve signaling

Furthermore, cerebellarthalamicbasal gangliacortical circuits have been implicated in reward-based learning (127), so their altered function may provide an explanation for the significant association between bipolar illness and substance use disorders

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4 Discussion This systematic review and meta-analysis provide a comparative evaluation of oral, sublingual, and intramuscular (IM) vitamin B12 supplementation in the management of B12 deficiency