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Generally, proteasomal proteolysis is a multi-enzyme process in which the covalent conjugation of ubiquitin to substrates induces degradation by the proteasome [19]

Higher doses of EPA (a specific omega-3) seem linked to better results

Ebselen is therefore a potent bifunctional pharmacological chaperone for SOD1 that combines properties of the SOD1 chaperone hCCS and the recently licenced antioxidant drug, edaravone