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The number of neutrophils in the outer region of interest (extravasated neutrophils) was normalized by the maximum number of neutrophils in the inner region of interest (un-extravasated neutrophils) across all time points for that lumen

Genomics 2017, 114

Excessive ROS activates c-Jun N-terminal kinase (JNK), which subsequently phosphorylates and stabilizes the tumor suppressor p53

De Leo E, Elmonem MA, Berlingerio SP, Berquez M, Festa BP, Raso R, Bellomo F, Starborg T, Janssen MJ, Abbaszadeh Z, Cairoli S, Goffredo BM, Masereeuw R, Devuyst O, Lowe M, Levtchenko E, Luciani A, Emma F, Rega LR (2020) Cell-based phenotypic drug screening identifies luteolin as candidate therapeutic for nephropathic cystinosis