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Description

Generally, mitochondrial respiration control, including oxygen consumption rate (OCR) and respiratory control ratio (RCR), is utilized to measure the mitochondrial function in diverse cell populations (Javadov et al., 2006, 2009)

PROTAC-degrading agents are a new direction in drug development for targeting GPx4

Rumah Sakit Nasional Dr

Notably, SLC27A5 negatively correlates with GSR, and genetic or pharmacological inhibition of GSR strengthens the efficacy of sorafenib through GSH depletion and the accumulation of lipid peroxide products in SLC27A5-knockout and sorafenib-resistant HCC cells