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doi: 10.1093/nar/gkab440 46 AkagawaM

Varelas, F

Reduced Systemic Inflammation The stack is researched for its capacity to reduce inflammatory cytokines and improve antioxidant defenses, supporting overall metabolic health and tissue protection

However, a recent study suggested that, rather than inducing R-loop formation, the transcriptional burst triggered by oncogenic RAS leads to H3K27me3- and HP1-associated chromatin compaction, thereby resulting in replication fork stalling and cell death 11