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Description

Mice were housed in groups (25 siblings) at 2224 C with a 12 h light-dark cycle and ad libitum access to regular chow diet and water

The other authors declared that there are no conflicts of interest

In this section, we present a summary of the mechanisms and critical regulators associated with ferroptosis from various aspects including iron metabolism, SystemX c /glutathione axis, and lipid peroxidation regulation (Figure 1)