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Metabolism : N-acetylcysteine is deacetylated to cysteine in the liver and vascular endothelium

It is recommended for high-risk screening populations (e.g., BRCA mutation carriers), preoperative staging, evaluation of treatment response, and problem-solving in inconclusive cases

One pathway that might mediate the sensitization to excitotoxic stimuli downstream of the activation of extrasynaptic NMDA receptors was identified as activation of p38 MAPK (Fan et al., 2012)

Data availability The authors declare that all the relevant data supporting the findings of the study are available in the article and its Supplementary Information files, or from the corresponding author upon request