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Through thick and thin: wasting, obesity, and TNF alpha

Dodaci ishrani nisu zamena za raznovrsnu ishranu, zdrav i izbalansiran nain ivota

Nezu J, Tamai I, Oku A, Ohashi R, Yabuuchi H, Hashimoto N, Nikaido H, Sai Y, Koizumi A, Shoji Y, Takada G, Matsuishi T, Yoshino M, Kato H, Ohura T, Tsujimoto G, Hayakawa J, Shimane M, Tsuji A: Primary systemic carnitine deficiency is caused by mutations in a gene encoding sodium ion-dependent carnitine transporter

The gut-liver axis becomes pathologically altered in NAFLD due to increased intestinal permeability, enabling translocation of microbial products into the liver and exacerbating inflammation