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Increased iron in brain tissue causes reactive oxygen species (ROS) formation via Fenton reaction, inducing ferroptosis and finally leading to neurodegeneration (Kim et al., 2015

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Antioxidant chemicals: A number of intracellular reducing agents, such as ascorbate, vitamin E, and -carotene, are able to reduce and, thereby, detoxify reactive oxygen intermediates in the laboratory

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Genetic Dys-Regulation of Astrocytic Glutamate Transporter EAAT2 and Its Implications in Neurological Disorders and Manganese Toxicity

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