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However, although its antidepressant effects have been demonstrated through other mechanisms, its anti-inflammatory and anti-ferroptotic properties remain to be validated in depressive models

Low dose naltrexone may result in opioid withdrawal symptoms or may decrease the effectiveness of opioids

86 ABC drug transporters are closely connected to metabolic pathways and using ATP, actively pump endogenous metabolites and cytotoxic drugs out of tumor cells and SLC transporters mediate the influx of cytotoxic drugs into cells

Histones, particularly histones H3 and H4, are important in the modulation of gene expression