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Other studies have shown that the coordinated modulation of STAT6 and p38 MAPK exhibited potential effects on the induction of IL4 and IL13 and that p38 MAPK could directly regulate the activity of the transactivation domain of STAT6 [47,48,49]

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This is one of the few human clinical data points for BPC-157 and, while small, it supports the direction of the preclinical work