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A lack of sleep is also likely to be a factor in childhood obesity

Recombinant vaccinia virus (W) engineered to express the gene for murine IL-4 was poorly cleared compared with control W

It is worth noting that while this hAOX metabolism was observed in this study, the half-lives of the compounds screened in human liver cytosol were high (90 minutes), and therefore further work is needed to establish the relevance of hAOX metabolism in the overall clearance of PROTAC molecules