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This was a small sample-sized study, and larger randomized controlled studies are needed to confirm this new possible mechanism of action involving carnitine supplements and increased risk of cardiovascular disease

Manjunathan T, Guru A, Arokiaraj J, Gopinath P (2021) 6-Gingerol and semisynthetic 6Gingerdione counteract oxidative stress induced by ROS in zebrafish

This hypercatabolism is evident by our data demonstrating depletion of amino acids and upregulation of the urea cycle as judged by elevated levels of urea cycle metabolites such as citrulline

Central facial redness and telangiectasias are also typically present, though less pronounced