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The mitochondrial-encoded peptide MOTS-c translocates to the nucleus to regulate nuclear gene expression in response to metabolic stress

GLP-1 (glucagon-like peptide-1) and GIP (glucose-dependent insulinotropic polypeptide) are both incretin hormones that your body produces naturally after eating

However, it lacks the clinical trial data and regulatory approval of GLP-1 agonists, and its effects may be more modest

Conclusion While many people can obtain sufficient B12 through a balanced diet rich in animal products, others may benefit significantly from B12 injections, especially those with dietary restrictions, absorption issues, or specific health conditions