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Research suggests the use of vitamin B12 supplements in those with kidney disease and a B12 deficiency, but fully understanding the risks and benefits of regular supplemental B12 in those without a deficit still requires more research

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That said, a PCAC vote is advisory, not binding, meaning real-world access for patients hasnt changed

Stem Cell Reports via PubMed (PMID 25937370), 2015 A search of the ClinicalTrials.gov registry for dihexa returns zero registered clinical trials the compound has never formally entered human testing