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Description

G.RenL.GuptaP.WeiL.et al (2018)

4:116ra6

This section reviews HDAC6's role in cancer development and progression through its influence on oxidative stress, emphasizing the therapeutic potential of HDAC6 inhibition in oncology

Consequently, these changes lead to increased oxidative stress, insulin resistance, inflammation, pancreatic -cell dysfunction with apoptosis, and eventually diabetic complications, including retinopathy, neuropathy, cardiomyopathy, microvascular complications, and nephropathy 47,48,49,50