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In addition, supplement with vitamin C could mitigate MIA-induced OA in rats [160]

These changes correlate with increased GSH levels and decreased ACSL4 expression, thus mitigating ferroptotic cell death in IL-1stimulated chondrocytes and preserving cartilage integrity (187)

In contrast, increased cell death was consistently observed across various lymphoid cell types, including tumor cells, underscoring that, within 3D gels, cell death, rather than cell cycle arrest, impedes lymphoid cell growth

Analysis of calcium ion (Ca 2+ ) levels in macrophages To detect the intracellular Ca 2+ content, 143B cells were incubated with PBS, Ru(II)-OH, NP2, and NP4 (Ru 10 M) for 6 h