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Further large-scale, long-term longitudinal trials are required to confirm whether these microbiota-based interventions directly translate into a reduced risk of clinical fracturesthe ultimate gold standard for OP treatment

After that, maintenance every 1218 months keeps the position

EXOs have been found to co-precipitate with other cellular components, including other extracellular vesicles, protein clumps, and even extremely abundant proteins, in a variety of biofluids such as plasma and serum

Research has shown that MSCs modified with synthetic miRNAs can improve the sensitivity of cancer cells to chemotherapy by transferring specific miRNAs through Exos [178,179,180]