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Bhattacharyya LH, Bhattacharyya PN (2016) Indigenous knowledge on the exploitation and utilization of medicinal plants by the Thengal Kachari tribe of Jorhat district, Assam, North-east India

At present, the best therapeutic strategy is to maintain good glycaemic control and early screening and to provide prompt treatment when micro- and macrovascular complications are detected.73 The continuous improvement in knowledge about the molecular and progression mechanisms of diabetic angiopathy is essential for the development of newer and better pharmacological therapies, targeted not only to just maintaining normoglycaemia but also to control the essential factors that contribute to the inflammatory state of diabetes

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The loss of MMP, elevated ROS, and ccf-mtDNA in the BD COs made them more prone to NLRP3 activation, which, in turn, further increases ccf-mtDNA therefore, causing the CO homeostasis to be disrupted both intracellularly and extracellularly