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16 Glutamate also appears to play a primary role in cortical spreading depolarization (CSD), believed to be the physiologic basis of migraine aura

doi: 10.2147/IDR.S232982 308 FarahaniFHMoraffahFSamadiNSharifzadehMMotasadizadehHVatanaraA

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Another study demonstrated that ALA administration significantly ameliorates scopolamine-induced memory impairment and exploratory behavior by reducing acetylcholinesterase activity and correcting the abnormal levels of amines in the hippocampus and prefrontal cortex [26]