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Since visual function depends on normal outer retina operations, which are susceptible to disruption due to the highly oxidative retinal environment, it is crucial to understand the role of the GSH redox system in maintaining homeostasis

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Together, these results indicate that while oncogenic -catenin reprograms zone 1/2 hepatocytes into zone 3-like hepatocytes and increases fatty acid metabolism, protein catabolism, and olefinic compound metabolism and decreases insulin-related gene expression, dietary protein restriction is associated with transcriptional changes in the opposite direction for the same pathways across all hepatocytes

Hothorn M, Wachter A, Gromes R, Stuwe T, Rausch T, Scheffzek K (septiembre de 2006)