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Description

Delineating the role of glutathione peroxidase 4 in protecting cells against lipid hydroperoxide damage and in Alzheimers disease

doi:10.1074/jbc.M116.752469

Tissue Repair and Recovery Research Beyond cosmetic applications, the peptide has been studied extensively in wound repair models

GPX4 converts GSH into oxidized glutathione (GSSG) and reduces the cytotoxic lipid peroxides (L-OOH) generated from membrane polyunsaturated fatty acids (PUFAs) to the corresponding alcohols (L-OH)