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Thats why figuring out where there are challenges in the cycle and how to help it perform better will significantly improve our health

Following its synthesis from acetyl-CoA and oxaloacetate by citrate synthase, citrate may either continue through the TCA cycle or be exported to the cytosol via a specific transporter, depending on the cells energetic and biosynthetic state

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Chronic zinc toxicity can lead to disturbances in copper metabolism causing low copper status, which affects iron distribution and causes anaemia, red blood cell microcytosis, neutropenia and reduced immune function [150, 151]