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In addition, Flag-MTR4 at several concentrations was transfected into the U251 cells to elevate the expression of MTR4 to different extents

Additionally, COMT , the methyltransferase responsible for inactivating catechol estrogen through DNA methylation, exhibits promoter hypermethylation in ectopic endometriotic samples, possibly reflecting an alteration of estrogen metabolism functions [85]

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Some antioxidants were found to sensitize cancer cells to normal cancer treatments and impart synergistic effects with standard radio- and chemotherapy [58,59,60, 82, 84, 89, 171,172,173]