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This research was funded by the National Training Program of Innovation and Entrepreneurship for Undergraduates (202410730173), the Fundamental Research Funds for the Central Universities of China (lzujbky-2024-1) and the Scientific Research Project of Health Industry in Gansu Province (GSWSKY2023-15)

The forestplots function of the metafor package in R was used to visualise boxplots of effect size and 95% confidence interval

Although the liver injury caused by Polygonum multiflorum has received attention, our previous studies have shown that the liver injury caused by Polygonum multiflorum is specific, and its main pharmacodynamic component, TSG, is safe and effective [271]

Zhang B-C, Li Z, Xu W, Xiang C-H, Ma Y-F (2018) Luteolin alleviates NLRP3 inflammasome activation and directs macrophage polarization in lipopolysaccharide-stimulated RAW264.7 cells