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During early CKD stages, rising EPO levels constitute a compensatory mechanism addressing hemoglobin decline from erythrocyte degradation

Non-steroidal anti-inflammatory drug induced acute kidney injury in the community dwelling general population and people with chronic kidney disease: systematic review and meta-analysis

9.9 Limitations of clinical implementations Preclinical testing of multi-target therapies poses additional challenges, as current animal models and testing protocols often do not accurately capture the complex interactions of multiple targets (256)

This allows the solution to remain stable for up to 28 days when refrigerated