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These diseases include retinal diseases, neurodegenerative diseases, osteoarthritis, cardiovascular diseases, cancer, and various reproductive disorders, significantly impacting the quality of life and lifespan of the elderly 56

Expression and purification of GSTO1 for crystallization For crystallization, GSTO1 residues 1241 were cloned into an expression construct containing an N-terminal 6xHis tag followed by a tobacco etch virus (TEV) protease cleavage site and expressed in E

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Upon binding to target proteins, the antibody pairs come into proximity, leading to hybridization and extension of the DNA reporter barcode