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The structural evidence here also provides no comment on the frequency of this mechanism in vivo

doi: 10.1126/science.1090148 [DOI] [PubMed] [Google Scholar] 43

It has been reported that the NLRP3 inflammasome in microglia can regulate the activation of A1 astrocytes, thereby modulating neurotoxic functions (Li et al., 2022b)

While there are not any clinical studies looking at curcumin use in endometriosis-related symptom management, in vitro and animal studies show potential