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7-chloro-4-(phenylselanyl) quinoline prevents dopamine depletion in a Drosophila melanogaster model of Parkinsons-like disease

Most of patients (897, 97.5%) in IFN group are classified as ChildPugh class A at baseline, and the rest (23, 2.5%) are classified as ChildPugh class B, while in Nuc group, there are 930 (90.8%), 79 (7.7%) and 15 (1.5%) patients in ChildPugh class A, B and C, respectively

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Next, proteolytic cleavage of disulfide bonds by furin family proteins result in generation of two characteristic proteins including N -terminal long dimeric and disulfide-linked propeptide, known as latency-associated peptide (LAP) and C-terminal short dimeric disulfide-linked polypeptide, known as mature TGF- (Ten Dijke and Arthur, 2007