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482 This finding further highlights the complex interplay between zinc, ROS, and endogenous antioxidant defenses regulated by NRF2

Furthermore, the strong negative charge on the noncanonical S -sulfonate, as well as the presence of arginine residues R370 and R413 in the Rhod active site, suggests that the interaction between the PDO and Rhod domain is facilitated by electrostatic steering of the loop

As previously described, the roGFP probe is already partially oxidized under standard temperature conditions, which is due to a lower glutathione redox potential (Figure 3, Meyer et al., 2007)

RT-PCR was not performed due to lack of available testing materials