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Proc West Pharmacol Soc 38: 911

Because milk thistle belongs to the Asteraceae/Compositae plant family, individuals with known allergies to ragweed, chrysanthemums, marigolds, or daisies should avoid this product, as it may trigger an allergic reaction

Avoid Active Skincare Ingredients: Products containing retinol, AHA, BHA, vitamin C, or skin-lightening agents should be avoided for at least 48 hours after the treatment

That means that flies that were heterozygous for the Adh allele (one copy of the Adh null allele and one copy of the Adh Wild type allele) gave very similar phenotypical alcohol tolerance as the homozygous dominant flies (two copies of the wild type Adh allele)