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These endogenous antioxidants include enzymes such as superoxide dismutase (SOD), catalase, and glutathione peroxidase, as well as small molecules such as glutathione and uric acid

Relative transcript level was calculated according to the method of Actin was used as a reference gene

These data suggest that acute lung injury caused by exposure to HMG may be related partially to complement mediated pathways and the generation by neutrophils of toxic oxygen species The data indicate that NAC is an effective antidote against HMG-induced acute lung injury in the rat