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189 In contrast, from a prophylactic approach, another research group proposed what they deemed a cost-effective approach of yearly injections of 1000 g of vitamin B12 to every patient on metformin to reduce the risk of deficiency and also stated that this could remove the requirement for annual screening, though this has not been empirically tested

It isrequired by the immune system for two important reasons: it protects host cellsthrough its antioxidant mechanism and it provides optimal functioning of lymphocytes

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doi: 10.1007/s11010-023-04871-4 70 ZhangXJiLLiMO