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In an evolutionary distinction, mammalian cells typically operate unidirectionally, i.e., they can convert homocysteine to cysteine, but not the other way round (Finkelstein, 1990)

Glucocorticoids are widely known for their anti-inflammatory characteristics, but due to their ubiquitous action profile, their therapeutic use can lead to off-target effects

Plusieurs essais cliniques ont effectivement observ une baisse modeste de l'indice de mlanine aprs supplmentation orale, mais ces rsultats restent fragiles : chantillons rduits, htrognit des formes et des dosages, effets limits certaines zones cutanes