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It protects cells from oxidative stress and supports immune function by bolstering other antioxidants

The predictions that it yields, like those obtained by homology modeling, are rigid

Moreover, the findings that mice with neutrophil-specific Gpx4 haploinsufficiency recapitulate key clinical features of human SLE, including autoantibodies, neutropenia, skin lesions and proteinuria, and that the treatment with a specific ferroptosis inhibitor significantly ameliorates disease severity in lupus-prone mice reveal the role of neutrophil ferroptosis in lupus pathogenesis

R.: Links between the Amundsen Sea Low and sea ice in the Ross Sea: seasonal and interannual relationships, Clim