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Rotenone (1.5 mg/kg, subcutaneously, three times per week), LPS (0.2 mg/kg, intraperitoneally, daily), or LPS plus rotenone was given alone or in combination with cannabis (20 mg/kg, expressed as 9 -tetrahydrocannabinol, subcutaneously daily) for 2 weeks

This shrinkage can reduce the brain's ability to form new memories, process information, and regulate emotions, contributing to cognitive decline

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enzymatic antioxidants like superoxide dismutase (SOD), catalase, and glutathione peroxidase, hydrogen's advantage lies in its effectiveness regardless of enzyme expression levels, cofactor availability, or cellular energy status