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Surprisingly, we still detected an induction effect of DMF on most of the factors studied despite NRF2 silencing (Fig

10.1016/j.bbagen.2012.09.008 [DOI] [PMC free article] [PubMed] [Google Scholar] Mak T

Consistently, HIF1A also promotes GSH synthesis through transcriptional activation of GCLM and SLC7A11 , and pharmacological inhibition of SLC7A11 with erastin or sorafenib exacerbates cuproptosis 177,178