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10.1016/s0014-2999(97)01033-9 121 SikiricP.SeiwerthS.MiseS.StaresinicM.BedekovicV.ZarkovicN.et al (2003)

The PI3K was demonstrated to be involved in MOR desensitization on the inhibition of voltage-gated calcium channels induced by chronic morphine treatment (Konig et al., 2010)