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& Romero, R

In this review, we provide a comprehensive overview of the current understanding on the mechanisms underlying the tubular toxicity of ultrafiltered proteins in the setting of proteinuric chronic kidney diseases

pDCs, Plasmacytoid Dendritic Cells

This modification can affect both pre-miRNA processing and the splicing of arsenic-induced ncRNAs, leading to disrupted miRNA maturation and function ( ATO upregulates the expression of miR-21 in LX-2 cells, while simultaneously downregulating PTEN expression