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Still, the practice of using glutathione for skin whitening persists, with IV glutathione being administered locally and shipped internationally

Moreover, the possibility that AITC in planta can interact with oxidized glutathione -as it was shown in vitro 77 - in addition to the reduced form also needs to be investigated

J Nanobiotechnol 21(1):452 Yang Z et al (2021) The transcription factors CREBH, PPARa, and FOXO1 as critical hepatic mediators of diet-induced metabolic dysregulation

In contrast, GSSG is less susceptible to decomposition in aqueous solution and is suitable for use in liquid form, although the skin-whitening effect of topical GSSG is unknown